Alessia Melani Selected Research

Purinergic P1 Receptors (Adenosine Receptor)

3/2014	Low doses of the selective adenosine A2A receptor agonist CGS21680 are protective in a rat model of transient cerebral ischemia.
1/2014	Adenosine receptors in cerebral ischemia.
1/2008	Regulation of A(2A) adenosine receptor expression and functioning following permanent focal ischemia in rat brain.
12/2007	Adenosine A2A receptors and brain injury: broad spectrum of neuroprotection, multifaceted actions and "fine tuning" modulation.

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Alessia Melani Research Topics

Disease

13	Ischemia 01/2018 - 01/2003
7	Brain Ischemia (Cerebral Ischemia) 01/2018 - 11/2005
6	Stroke (Strokes) 08/2015 - 12/2007
3	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 08/2015 - 02/2006
2	Transient Ischemic Attack 01/2018 - 03/2014
2	Hypotension (Low Blood Pressure) 01/2014 - 10/2010
2	Inflammation (Inflammations) 10/2011 - 10/2011
2	Spinal Cord Injuries (Spinal Cord Injury) 04/2011 - 12/2009
2	Parkinson Disease (Parkinson's Disease) 12/2007 - 03/2003
2	Huntington Disease (Huntington's Disease) 12/2007 - 07/2003
1	Bradycardia 01/2014
1	Neuroinflammatory Diseases 01/2014
1	Ischemic Stroke 01/2014
1	Pleurisy (Pleuritis) 10/2011
1	Pneumonia (Pneumonitis) 10/2011
1	Experimental Arthritis 10/2011
1	Lung Injury 10/2011
1	Necrosis 10/2011
1	Arthritis (Polyarthritis) 10/2011
1	Demyelinating Diseases (Demyelinating Disease) 04/2011
1	Wounds and Injuries (Trauma) 04/2011
1	Cognitive Dysfunction 10/2010
1	Reperfusion Injury 05/2010
1	Multiple Sclerosis 12/2007
1	Nervous System Diseases (Neurological Disorders) 12/2007
1	Alzheimer Disease (Alzheimer's Disease) 12/2007
1	Dementia (Dementias) 12/2007
1	Neurodegenerative Diseases (Neurodegenerative Disease) 12/2007
1	Brain Injuries (Brain Injury) 12/2007
1	Brain Infarction 07/2006
1	Infarction (Infarctions) 07/2006
1	Glioma (Gliomas) 07/2003
1	Neoplasms (Cancer) 07/2003

Drug/Important Bio-Agent (IBA)

10	Adenosine (Adenocard)FDA LinkGeneric 01/2016 - 01/2003
10	Adenosine A2A Receptor (Adenosine A2A Receptors)IBA 08/2015 - 01/2003
4	Glutamic Acid (Glutamate)FDA Link 01/2016 - 07/2003
4	5- amino- 7- (2- phenylethyl)- 2- (2- furyl)pyrazolo(4,3- e)- 1,2,4- triazolo(1,5- c)pyrimidineIBA 08/2015 - 01/2003
4	Purinergic P1 Receptors (Adenosine Receptor)IBA 03/2014 - 12/2007
4	2- (4- (2- carboxyethyl)phenethylamino)- 5'- N- ethylcarboxamidoadenosineIBA 03/2014 - 05/2010
3	Adenosine Triphosphate (ATP)IBA 01/2016 - 11/2005
2	Neuroprotective AgentsIBA 01/2018 - 01/2016
2	CytokinesIBA 01/2018 - 10/2011
2	Inflammation MediatorsIBA 01/2016 - 01/2014
2	P-2 (P 2)IBA 10/2011 - 05/2010
1	Histamine (Histamine Dihydrochloride)FDA Link 01/2018
1	1- ((5- chloro- 1H- indol- 2- yl)carbonyl)- 4- methylpiperazineIBA 01/2018
1	Histamine H4 ReceptorsIBA 01/2018
1	NucleotidasesIBA 01/2012
1	Collagen Type II (Type II Collagen)IBA 10/2011
1	CarrageenanIBA 10/2011
1	Cell Adhesion MoleculesIBA 10/2011
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 10/2011
1	P-SelectinIBA 10/2011
1	Mitogen-Activated Protein KinasesIBA 04/2011
1	Adenosine A2 Receptor AgonistsIBA 04/2011
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 10/2010
1	Dipyridamole (Persantine)FDA LinkGeneric 10/2010
1	Fibrinolytic Agents (Antithrombotic Agents)IBA 10/2010
1	GTP-Binding Proteins (G-Protein)IBA 01/2008
1	LigandsIBA 12/2007
1	Cibacron Blue F 3GAIBA 07/2006
1	Purinergic P2X7 ReceptorsIBA 07/2006
1	p38 Mitogen-Activated Protein KinasesIBA 02/2006
1	cresyl violetIBA 02/2006
1	alpha,beta-methyleneadenosine 5'-diphosphateIBA 11/2005
1	purineIBA 07/2003
1	Quinolinic AcidIBA 07/2003
1	Excitatory Amino AcidsIBA 01/2003

Therapy/Procedure

2	Laminectomy 04/2011 - 12/2009
1	Drug Therapy (Chemotherapy) 01/2014
1	Intravenous Administration 10/2010